Purose 4 Fast Flow and Purose 6 Fast Flow are blank microspheres obtained by crosslink based on 4 B and 6 B. Purose Fast Flow series retain the excellent hydrophilicity and large grid structure of natural polysaccharide compounds. They have good compatibility with bioactive macromolecules, and they have the characteristics of high strength, no non-specific adsorption and fast operation flow velocity, etc. These products are widely used in laboratory-scale preparation of virus, protein, nucleic acid, polypeptide, polysaccharide, or other biological macromolecules, as well as in large-scale industrial production of biopharmaceutical and biological engineering field.